SPRB insider transaction filings

SPRUCE BIOSCIENCES, INC. — 50 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-07-29. Screen SPRB transaction legs live →

Insider transaction summary — last 90 days

2026-06-24 to 2026-09-22, from the filings listed below: 2 Form 4 filings. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By insider — same window

Open-market purchase/sale legs on non-derivative securities, grouped by the filing's reporting owner(s); joint filings appear once. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

InsiderFilingsPurchases (P)Sales (S)Other legs
Quartel Adrian W — Chief Medical Officer11
Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, Director11

Recent Form 4 filings — SPRUCE BIOSCIENCES, INC.

FiledFormInsiderReported transactionsSource
2026-07-294Quartel Adrian W — Chief Medical OfficerGrant/award (A): 13,000 (derivative) @ $0EDGAR
2026-07-094Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorGrant/award (A): 266 @ $4.53EDGAR
2026-05-264Walbert Keli — DirectorGrant/award (A): 1,700 (derivative) @ $0EDGAR
2026-05-264Barretto-Ko Percival — DirectorGrant/award (A): 1,700 (derivative) @ $0EDGAR
2026-05-264SIMPSON CAMILLA V — DirectorGrant/award (A): 1,700 (derivative) @ $0EDGAR
2026-05-264GREY MICHAEL G — Executive Chairman, DirectorGrant/award (A): 1,700 (derivative) @ $0EDGAR
2026-05-264SPIEGELMAN DANIEL K — DirectorGrant/award (A): 1,700 (derivative) @ $0EDGAR
2026-03-094Hooks Corwin Dale — Chief Commercial OfficerGrant/award (A): 11,000 (derivative) @ $0EDGAR
2026-01-214Ways Douglas Kirk — Interim Chief Medical Officer, DirectorOption exercise (M): 1,250 @ $0 · Grant/award (A): 5,000 (derivative) @ $0 · Option exercise (M): 1,250 (derivative) @ $0 · Grant/award (A): 266 (derivative) · Disposition to issuer (D): 266 (derivative) · Grant/award (A): 400 (derivative) · +1 moreEDGAR
2026-01-054Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorGrant/award (A): 4,690 @ $4.53EDGAR
2025-12-174Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorOption exercise (M): 1,480 @ $0 · Tax withholding (F): 752 @ $80.67 · Option exercise (M): 1,196 @ $0 · Tax withholding (F): 608 @ $80.67 · Grant/award (A): 1,666 (derivative) · Disposition to issuer (D): 1,666 (derivative) · +2 moreEDGAR
2025-12-174Gharib Samir M. — PRESIDENT AND CFOOption exercise (M): 496 @ $0 · Tax withholding (F): 178 @ $80.67 · Option exercise (M): 513 @ $0 · Tax withholding (F): 184 @ $80.67 · Option exercise (M): 496 (derivative) @ $0 · Option exercise (M): 513 (derivative) @ $0EDGAR
2025-12-154Walbert Keli — DirectorGrant/award (A): 3,400 (derivative) @ $0EDGAR
2025-12-154Barretto-Ko Percival — DirectorGrant/award (A): 800 (derivative) · Disposition to issuer (D): 800 (derivative)EDGAR
2025-12-154Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorGrant/award (A): 10,000 (derivative) · Disposition to issuer (D): 10,000 (derivative)EDGAR
2025-12-154SIMPSON CAMILLA V — DirectorGrant/award (A): 173 (derivative) · Disposition to issuer (D): 173 (derivative) · Grant/award (A): 309 (derivative) · Disposition to issuer (D): 309 (derivative) · Grant/award (A): 362 (derivative) · Disposition to issuer (D): 362 (derivative) · +4 moreEDGAR
2025-12-154Gharib Samir M. — PRESIDENT AND CFOGrant/award (A): 1,579 (derivative) · Disposition to issuer (D): 1,579 (derivative) · Grant/award (A): 953 (derivative) · Disposition to issuer (D): 953 (derivative) · Grant/award (A): 733 (derivative) · Disposition to issuer (D): 733 (derivative) · +4 moreEDGAR
2025-12-154GREY MICHAEL G — Executive Chairman, DirectorGrant/award (A): 387 (derivative) · Disposition to issuer (D): 387 (derivative) · Grant/award (A): 1,255 (derivative) · Disposition to issuer (D): 1,255 (derivative) · Grant/award (A): 1,499 (derivative) · Disposition to issuer (D): 1,499 (derivative) · +6 moreEDGAR
2025-12-154SPIEGELMAN DANIEL K — DirectorGrant/award (A): 458 (derivative) · Disposition to issuer (D): 458 (derivative) · Grant/award (A): 88 (derivative) · Disposition to issuer (D): 88 (derivative) · Grant/award (A): 400 (derivative) · Disposition to issuer (D): 400 (derivative)EDGAR
2025-12-124Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorOption exercise (M): 1,196 @ $0 · Tax withholding (F): 428 @ $85.67 · Option exercise (M): 4,950 @ $0 · Tax withholding (F): 2,194 @ $88.41 · Option exercise (M): 1,196 (derivative) @ $0 · Grant/award (A): 19,800 (derivative) @ $0 · +1 moreEDGAR
2025-12-124Gharib Samir M. — PRESIDENT AND CFOOption exercise (M): 514 @ $0 · Tax withholding (F): 184 @ $85.67 · Option exercise (M): 1,900 @ $0 · Tax withholding (F): 680 @ $88.41 · Option exercise (M): 514 (derivative) @ $0 · Grant/award (A): 7,600 (derivative) @ $0 · +1 moreEDGAR
2025-10-224Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorOption exercise (M): 4,784 @ $0 · Tax withholding (F): 1,539 @ $148.16 · Grant/award (A): 4,784 (derivative) @ $0 · Option exercise (M): 4,784 (derivative) @ $0EDGAR
2025-10-224Gharib Samir M. — PRESIDENT AND CFOOption exercise (M): 2,053 @ $0 · Tax withholding (F): 661 @ $148.16 · Grant/award (A): 2,053 (derivative) @ $0 · Option exercise (M): 2,053 (derivative) @ $0EDGAR
2025-10-154Parkman Healthcare Partners LLC — 10% owner
Martinez Gregory — 10% owner
Purchase (P): 256 @ $17.91 · Sale (S): 232 @ $19.33 · Sale (S): 25 @ $17.46EDGAR
2025-10-084Parkman Healthcare Partners LLC — 10% ownerPurchase (P): 256 @ $17.91 · Sale (S): 232 @ $19.33 · Sale (S): 25 @ $17.46EDGAR
2025-07-244SIMPSON CAMILLA V — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244Barretto-Ko Percival — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244Ways Kirk — Interim Chief Medical Officer, DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244Muralidhar Bali — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244Aynechi Tiba — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244GREY MICHAEL G — Executive Chairman, DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2025-07-244SPIEGELMAN DANIEL K — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-12-204Charlton Ralph William III — CHIEF MEDICAL OFFICEROption exercise (M): 106,400 @ $0 · Tax withholding (F): 37,964 @ $0.54 · Option exercise (M): 26,600 @ $0 · Tax withholding (F): 9,491 @ $0.39 · Option exercise (M): 31,750 @ $0 · Tax withholding (F): 11,329 @ $0.39 · +3 moreEDGAR
2024-12-204Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorOption exercise (M): 358,800 @ $0 · Tax withholding (F): 128,020 @ $0.54 · Option exercise (M): 89,700 @ $0 · Tax withholding (F): 32,005 @ $0.39 · Option exercise (M): 111,000 @ $0 · Tax withholding (F): 39,605 @ $0.39 · +3 moreEDGAR
2024-12-204Gharib Samir M. — PRESIDENT AND CFOOption exercise (M): 154,000 @ $0 · Tax withholding (F): 54,948 @ $0.54 · Option exercise (M): 38,500 @ $0 · Tax withholding (F): 13,737 @ $0.39 · Option exercise (M): 37,250 @ $0 · Tax withholding (F): 13,291 @ $0.39 · +3 moreEDGAR
2024-05-244Ways Kirk — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244SIMPSON CAMILLA V — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244Muralidhar Bali — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244Barretto-Ko Percival — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244Aynechi Tiba — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244GREY MICHAEL G — Executive Chairman, DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-05-244SPIEGELMAN DANIEL K — DirectorGrant/award (A): 30,000 (derivative) @ $0EDGAR
2024-03-254Novo Holdings A/S — 10% ownerSale (S): 465,021 @ $0.75EDGAR
2024-03-204Novo Holdings A/S — 10% ownerSale (S): 842,020 @ $0.77 · Sale (S): 593,000 @ $0.76 · Sale (S): 359,979 @ $0.73EDGAR
2024-03-184Charlton Ralph William III — CHIEF MEDICAL OFFICERGrant/award (A): 106,400 (derivative) @ $0EDGAR
2024-03-184Szwarcberg Javier B. — CHIEF EXECUTIVE OFFICER, DirectorGrant/award (A): 358,800 (derivative) @ $0EDGAR
2024-03-184Gharib Samir M. — PRESIDENT AND CFOGrant/award (A): 154,000 (derivative) @ $0EDGAR
2024-03-184Novo Holdings A/S — 10% ownerSale (S): 1,912,316 @ $0.89EDGAR
2024-01-034Charlton Ralph William III — Chief Medical OfficerGrant/award (A): 9,361 @ $0.98EDGAR
2024-01-034Gharib Samir M. — President & CFOGrant/award (A): 11,255 @ $0.98EDGAR

Recent 8-K events — SPRUCE BIOSCIENCES, INC.

FiledFormItems reportedSource
2026-08-128-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-07-278-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain OfficersEDGAR
2026-05-268-K5.07 — Submission of Matters to a Vote of Security Holders
9.01 — Financial Statements and Exhibits
EDGAR
2026-05-138-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-04-228-K1.01 — Entry into a Material Definitive Agreement
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-208-K1.02 — Termination of a Material Definitive AgreementEDGAR
2026-03-098-K1.01 — Entry into a Material Definitive Agreement
1.02 — Termination of a Material Definitive Agreement
2.02 — Results of Operations and Financial Condition
5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
9.01 — Financial Statements and Exhibits
EDGAR
2026-02-058-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-01-088-K1.01 — Entry into a Material Definitive Agreement
2.02 — Results of Operations and Financial Condition
2.03 — Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant
3.02 — Unregistered Sales of Equity Securities
7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2025-12-158-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain OfficersEDGAR
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