SION insider transaction filings
Sionna Therapeutics, Inc. — 50 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-09-21. Screen SION transaction legs live →
Insider transaction summary — last 90 days
2026-06-24 to 2026-09-22, from the filings listed below: 10 Form 4 filings. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.
- Open-market purchases (code P, non-derivative): none reported.
- Open-market sales (code S, non-derivative): 7 legs across 6 filings by 10 insiders — 3,862,585 shares, $40,532,247 total (shares × price as filed).
- Other reported legs (grants, option exercises, tax withholding, gifts, derivative-security transactions, …): 18.
- Largest priced transaction: sale of 3,415,011 shares @ $6.32 ($21,582,870) by RA CAPITAL MANAGEMENT, L.P., filed 2026-09-21.
By insider — same window
Open-market purchase/sale legs on non-derivative securities, grouped by the filing's reporting owner(s); joint filings appear once. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.
| Insider | Filings | Purchases (P) | Sales (S) | Other legs |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner & RA Capital Healthcare Fund LP — Director & RA Capital Nexus Fund, L.P. — Director & RA Capital Nexus Fund III, L.P. — Director & Kolchinsky Peter — Director, 10% owner & Shah Rajeev M. — Director, 10% owner | 1 | — | 2 legs · 3,448,811 sh · $21,835,018 | — |
| ORBIMED ADVISORS LLC — Director & OrbiMed Capital GP VIII LLC — Director | 2 | — | 2 legs · 201,762 sh · $9,125,183 | — |
| Thompson Peter A. — Director | 2 | — | 2 legs · 201,762 sh · $9,125,183 | — |
| Fitzpatrick Jennifer — CLO and Head of Program Mgmt. | 2 | — | 1 leg · 10,250 sh · $446,862 | 6 |
| Cloonan Michael — President & CEO, Director | 1 | — | — | 4 |
| McKee Charlotte — CMO and Head of R&D | 1 | — | — | 4 |
| Ridloff Elena — CFO and CBO | 1 | — | — | 4 |
Recent Form 4 filings — Sionna Therapeutics, Inc.
| Filed | Form | Insider | Reported transactions | Source |
|---|---|---|---|---|
| 2026-09-21 | 4 | RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner RA Capital Healthcare Fund LP — Director RA Capital Nexus Fund, L.P. — Director RA Capital Nexus Fund III, L.P. — Director Kolchinsky Peter — Director, 10% owner Shah Rajeev M. — Director, 10% owner | Sale (S): 3,415,011 @ $6.32 · Sale (S): 33,800 @ $7.46 | EDGAR |
| 2026-09-18 | 4 | Ridloff Elena — CFO and CBO | Grant/award (A): 47,269 @ $0 · Grant/award (A): 47,268 @ $0 · Grant/award (A): 165,440 (derivative) @ $0 · Disposition to issuer (D): 165,440 (derivative) @ $0 | EDGAR |
| 2026-09-18 | 4 | Fitzpatrick Jennifer — CLO and Head of Program Mgmt. | Grant/award (A): 28,133 @ $0 · Grant/award (A): 28,132 @ $0 · Grant/award (A): 103,140 (derivative) @ $0 · Disposition to issuer (D): 103,140 (derivative) @ $0 | EDGAR |
| 2026-09-18 | 4 | McKee Charlotte — CMO and Head of R&D | Grant/award (A): 50,000 @ $0 · Grant/award (A): 50,000 @ $0 · Grant/award (A): 155,700 (derivative) @ $0 · Disposition to issuer (D): 155,700 (derivative) @ $0 | EDGAR |
| 2026-09-18 | 4 | Cloonan Michael — President & CEO, Director | Grant/award (A): 109,025 @ $0 · Grant/award (A): 109,025 @ $0 · Grant/award (A): 436,100 (derivative) @ $0 · Disposition to issuer (D): 436,100 (derivative) @ $0 | EDGAR |
| 2026-07-09 | 4 | Thompson Peter A. — Director | Sale (S): 85,918 @ $44.86 | EDGAR |
| 2026-07-09 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 85,918 @ $44.86 | EDGAR |
| 2026-07-07 | 4 | Fitzpatrick Jennifer — Chief Legal Officer | Option exercise (M): 10,250 @ $6.11 · Sale (S): 10,250 @ $43.60 · Option exercise (M): 10,250 (derivative) @ $0 | EDGAR |
| 2026-07-02 | 4 | Thompson Peter A. — Director | Sale (S): 115,844 @ $45.50 | EDGAR |
| 2026-07-02 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 115,844 @ $45.50 | EDGAR |
| 2026-06-18 | 4 | Ruddy Marcella K. — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Fleming Harold Edward — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Viney Joanne L. — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Resnick Joshua — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Stelzer Laurie — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Booth Bruce — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Clancy Paul J — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Thompson Peter A. — Director | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner RA Capital Healthcare Fund LP — Director, 10% owner RA Capital Nexus Fund, L.P. — Director RA Capital Nexus Fund III, L.P. — Director Kolchinsky Peter — Director, 10% owner Shah Rajeev M. — Director, 10% owner | Grant/award (A): 17,340 (derivative) @ $0 | EDGAR |
| 2026-05-29 | 4 | Thompson Peter A. — Director | Sale (S): 101 @ $44.49 | EDGAR |
| 2026-05-29 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 101 @ $44.49 | EDGAR |
| 2026-05-11 | 4 | Thompson Peter A. — Director | Sale (S): 48,546 @ $44.61 · Sale (S): 59,767 @ $44.58 · Sale (S): 184,639 @ $46.22 | EDGAR |
| 2026-05-11 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 48,546 @ $44.61 · Sale (S): 59,767 @ $44.58 · Sale (S): 184,639 @ $46.22 | EDGAR |
| 2026-04-21 | 4 | Thompson Peter A. — Director | Sale (S): 52,397 @ $44.68 · Sale (S): 2,948 @ $44.52 | EDGAR |
| 2026-04-21 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 52,397 @ $44.68 · Sale (S): 2,948 @ $44.52 | EDGAR |
| 2026-04-16 | 4 | Thompson Peter A. — Director | Sale (S): 47,814 @ $44.51 · Sale (S): 235,863 @ $44.64 · Sale (S): 226,906 @ $45.34 | EDGAR |
| 2026-04-16 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 47,814 @ $44.51 · Sale (S): 235,863 @ $44.64 · Sale (S): 226,906 @ $45.34 | EDGAR |
| 2026-03-06 | 4 | Fitzpatrick Jennifer — Chief Legal Officer | Option exercise (M): 10,250 @ $6.11 · Sale (S): 10,250 @ $33.86 · Option exercise (M): 10,250 (derivative) @ $0 | EDGAR |
| 2026-02-04 | 4 | Thompson Peter A. — Director | Sale (S): 1,890 @ $44.57 · Sale (S): 29,063 @ $44.58 | EDGAR |
| 2026-02-04 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 1,890 @ $44.57 · Sale (S): 29,063 @ $44.58 | EDGAR |
| 2026-01-26 | 4 | TPG GP A, LLC — 10% owner COULTER JAMES G — 10% owner WINKELRIED JON — 10% owner | Sale (S): 250,000 @ $40 | EDGAR |
| 2026-01-06 | 4 | Beer Caroline Stark — Chief Business Officer | Grant/award (A): 139,340 (derivative) @ $0 | EDGAR |
| 2026-01-06 | 4 | Fitzpatrick Jennifer — Chief Legal Officer | Grant/award (A): 103,140 (derivative) @ $0 | EDGAR |
| 2026-01-06 | 4 | McKee Charlotte — Chief Medical Officer | Grant/award (A): 155,700 (derivative) @ $0 | EDGAR |
| 2026-01-06 | 4 | Ridloff Elena — CFO | Grant/award (A): 165,440 (derivative) @ $0 | EDGAR |
| 2026-01-06 | 4 | Cloonan Michael — President & CEO, Director | Grant/award (A): 436,100 (derivative) @ $0 | EDGAR |
| 2025-12-29 | 4 | Thompson Peter A. — Director | Sale (S): 33,356 @ $44.55 | EDGAR |
| 2025-12-29 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 33,356 @ $44.55 | EDGAR |
| 2025-12-19 | 4 | Thompson Peter A. — Director | Sale (S): 900 @ $44.50 · Sale (S): 100 @ $44.49 · Sale (S): 875 @ $44.49 | EDGAR |
| 2025-12-19 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 900 @ $44.50 · Sale (S): 100 @ $44.49 · Sale (S): 875 @ $44.49 | EDGAR |
| 2025-12-09 | 4 | Fitzpatrick Jennifer — Chief Legal Officer | Option exercise (M): 10,250 @ $6.11 · Sale (S): 10,250 @ $40.52 · Option exercise (M): 10,250 (derivative) @ $0 | EDGAR |
| 2025-11-26 | 4 | Thompson Peter A. — Director | Sale (S): 94,583 @ $44.54 · Sale (S): 11,890 @ $44.60 · Sale (S): 1,600 @ $44.49 | EDGAR |
| 2025-11-26 | 4 | ORBIMED ADVISORS LLC — Director OrbiMed Capital GP VIII LLC — Director | Sale (S): 94,583 @ $44.54 · Sale (S): 11,890 @ $44.60 · Sale (S): 1,600 @ $44.49 | EDGAR |
| 2025-11-24 | 4 | RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner RA Capital Healthcare Fund LP — Director, 10% owner RA Capital Nexus Fund, L.P. — Director RA Capital Nexus Fund III, L.P. — Director Kolchinsky Peter — Director, 10% owner Shah Rajeev M. — Director, 10% owner | Sale (S): 150 @ $39.89 · Sale (S): 1,235 @ $39.89 · Sale (S): 801 @ $39.89 · Sale (S): 947 @ $39.89 · Sale (S): 96 @ $40.50 · Sale (S): 788 @ $40.50 · +6 more | EDGAR |
| 2025-11-19 | 4 | RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner RA Capital Healthcare Fund LP — Director, 10% owner RA Capital Nexus Fund, L.P. — Director RA Capital Nexus Fund III, L.P. — Director Kolchinsky Peter — Director, 10% owner Shah Rajeev M. — Director, 10% owner | Sale (S): 2,182 @ $40.20 · Sale (S): 17,913 @ $40.20 · Sale (S): 11,626 @ $40.20 · Sale (S): 13,734 @ $40.20 · Sale (S): 1,701 @ $41.05 · Sale (S): 13,964 @ $41.05 · +18 more | EDGAR |
| 2025-10-28 | 4 | RA CAPITAL MANAGEMENT, L.P. — Director, 10% owner RA Capital Healthcare Fund LP — Director, 10% owner RA Capital Nexus Fund, L.P. — Director RA Capital Nexus Fund III, L.P. — Director Kolchinsky Peter — Director, 10% owner Shah Rajeev M. — Director, 10% owner | Sale (S): 14,116 @ $39.50 · Sale (S): 122,271 @ $39.50 · Sale (S): 66,672 @ $39.50 · Sale (S): 107,941 @ $39.50 · Sale (S): 3,624 @ $39.58 · Sale (S): 31,392 @ $39.58 · +2 more | EDGAR |
| 2025-10-22 | 4 | Cloonan Michael — President & CEO, Director | Option exercise (M): 13,324 @ $6.11 · Sale (S): 13,324 @ $34.44 · Option exercise (M): 30,049 @ $6.11 · Sale (S): 30,049 @ $35.63 · Option exercise (M): 22,895 @ $6.11 · Sale (S): 22,895 @ $36.60 · +6 more | EDGAR |
| 2025-10-21 | 4 | Booth Bruce — Director | Sale (S): 22,339 @ $32.69 · Sale (S): 4,688 @ $32.69 · Sale (S): 19,948 @ $33.87 · Sale (S): 4,187 @ $33.87 · Sale (S): 5,763 @ $34.91 · Sale (S): 1,210 @ $34.91 · +4 more | EDGAR |
| 2025-10-20 | 4 | Booth Bruce — Director | Sale (S): 8,596 @ $30.15 · Sale (S): 1,804 @ $30.15 · Sale (S): 45,117 @ $31.69 · Sale (S): 9,470 @ $31.69 · Sale (S): 73,296 @ $32.84 · Sale (S): 15,384 @ $32.84 · +12 more | EDGAR |
| 2025-10-17 | 4 | Cloonan Michael — President & CEO, Director | Option exercise (M): 14,775 @ $6.11 · Sale (S): 14,775 @ $31.11 · Option exercise (M): 10,225 @ $6.11 · Sale (S): 10,225 @ $31.46 · Option exercise (M): 200 @ $6.11 · Sale (S): 200 @ $34 · +3 more | EDGAR |
Recent 8-K events — Sionna Therapeutics, Inc.
| Filed | Form | Items reported | Source |
|---|---|---|---|
| 2026-09-14 | 8-K | ? 5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers 8.01 — Other Events 9.01 — Financial Statements and Exhibits | EDGAR |
| 2026-08-10 | 8-K | 8.01 — Other Events 9.01 — Financial Statements and Exhibits | EDGAR |
| 2026-08-06 | 8-K | 2.02 — Results of Operations and Financial Condition 9.01 — Financial Statements and Exhibits | EDGAR |
| 2026-06-18 | 8-K | 5.07 — Submission of Matters to a Vote of Security Holders | EDGAR |
| 2026-05-12 | 8-K | 2.02 — Results of Operations and Financial Condition 9.01 — Financial Statements and Exhibits | EDGAR |
| 2026-03-02 | 8-K | 2.02 — Results of Operations and Financial Condition 9.01 — Financial Statements and Exhibits | EDGAR |
| 2025-11-05 | 8-K | 2.02 — Results of Operations and Financial Condition 9.01 — Financial Statements and Exhibits | EDGAR |
| 2025-08-11 | 8-K | 2.02 — Results of Operations and Financial Condition 9.01 — Financial Statements and Exhibits | EDGAR |
| 2025-06-13 | 8-K | 5.07 — Submission of Matters to a Vote of Security Holders | EDGAR |
| 2025-06-04 | 8-K | 7.01 — Regulation FD Disclosure 9.01 — Financial Statements and Exhibits | EDGAR |
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