KPTI insider transaction filings

Karyopharm Therapeutics Inc. — 50 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-09-02. Screen KPTI transaction legs live →

Insider transaction summary — last 90 days

2026-06-24 to 2026-09-22, from the filings listed below: 2 Form 4 filings. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By insider — same window

Open-market purchase/sale legs on non-derivative securities, grouped by the filing's reporting owner(s); joint filings appear once. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

InsiderFilingsPurchases (P)Sales (S)Other legs
Poulton Stuart — EVP, Chief Development Officer11 leg · 189 sh · $1,342
Abate Kristin — Chief Accounting Officer11 leg · 19 sh · $38

Recent Form 4 filings — Karyopharm Therapeutics Inc.

FiledFormInsiderReported transactionsSource
2026-09-024Abate Kristin — Chief Accounting OfficerSale (S): 19 @ $2.02EDGAR
2026-07-304Poulton Stuart — EVP, Chief Development OfficerSale (S): 189 @ $7.10EDGAR
2026-05-264Su Zhen — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-264Oliger Christy J. — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-264Schor Chen — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-264Greene Barry E — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-264PAKIANATHAN DEEPIKA — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-264BOHLIN GAREN G — DirectorGrant/award (A): 15,508 @ $0EDGAR
2026-05-154Poulton Stuart — EVP, Chief Development OfficerGrant/award (A): 896 @ $0 · Sale (S): 403 @ $9.50EDGAR
2026-05-154Rangwala Reshma — EVP & Chief Medical OfficerGrant/award (A): 947 @ $0 · Sale (S): 408 @ $9.50EDGAR
2026-05-154Cheng Sohanya Roshan — EVP & Chief Commercial OfficerGrant/award (A): 947 @ $0 · Sale (S): 324 @ $9.50EDGAR
2026-05-154Abate Kristin — Chief Accounting OfficerGrant/award (A): 121 @ $0 · Sale (S): 53 @ $9.50EDGAR
2026-05-154Paulson Richard A. — President and CEO, DirectorGrant/award (A): 4,920 @ $0 · Sale (S): 2,203 @ $9.50EDGAR
2026-05-154Mano Michael — EVP, CLO&SecretaryGrant/award (A): 700 @ $0 · Sale (S): 266 @ $9.50EDGAR
2026-04-224Rangwala Reshma — EVP & Chief Medical OfficerSale (S): 449 @ $8.94EDGAR
2026-03-034Abate Kristin — Chief Accounting OfficerSale (S): 559 @ $9.41EDGAR
2026-03-034Poulton Stuart — EVP, Chief Development OfficerSale (S): 5,101 @ $9.41EDGAR
2026-03-034Cheng Sohanya Roshan — EVP & Chief Commercial OfficerSale (S): 4,604 @ $9.41EDGAR
2026-03-034Mano Michael — EVP, CLO&SecretarySale (S): 3,526 @ $9.41EDGAR
2026-03-034Rangwala Reshma — EVP & Chief Medical OfficerSale (S): 5,066 @ $9.41EDGAR
2026-03-034Paulson Richard A. — President and CEO, DirectorSale (S): 12,361 @ $9.41EDGAR
2026-02-194Poulton Stuart — EVP, Chief Development OfficerSale (S): 378 @ $8.63EDGAR
2026-02-094Paulson Richard A. — President and CEO, DirectorGrant/award (A): 81,060 @ $0EDGAR
2026-02-044Macomber Lori — EVP, CFO & TreasurerSale (S): 1,626 @ $6.30EDGAR
2026-02-034Cheng Sohanya Roshan — EVP & Chief Commercial OfficerGrant/award (A): 32,415 @ $0EDGAR
2026-02-034Rangwala Reshma — EVP & Chief Medical OfficerGrant/award (A): 32,415 @ $0EDGAR
2026-02-034Macomber Lori — EVP, CFO & TreasurerGrant/award (A): 32,415 @ $0EDGAR
2026-02-034Mano Michael — EVP, CLO&SecretaryGrant/award (A): 32,415 @ $0EDGAR
2026-02-034Poulton Stuart — EVP, Chief Development OfficerGrant/award (A): 32,415 @ $0EDGAR
2026-01-294Abate Kristin — Chief Accounting OfficerGrant/award (A): 92 @ $0 · Sale (S): 50 @ $7.03EDGAR
2026-01-224Abate Kristin — Chief Accounting OfficerSale (S): 265 @ $5.96EDGAR
2025-10-164Abate Kristin — Chief Accounting OfficerGrant/award (A): 12,799 @ $0EDGAR
2025-10-164Poulton Stuart — EVP, Chief Development OfficerGrant/award (A): 39,682 @ $0EDGAR
2025-10-164Mano Michael — SVP, General Counsel&SecretaryGrant/award (A): 43,650 @ $0EDGAR
2025-10-164Paulson Richard A. — President and CEO, DirectorGrant/award (A): 114,285 @ $0EDGAR
2025-10-164Cheng Sohanya Roshan — EVP & Chief Commercial OfficerGrant/award (A): 43,650 @ $0EDGAR
2025-10-164Macomber Lori — EVP, CFO & TreasurerGrant/award (A): 43,650 @ $0EDGAR
2025-10-034Abate Kristin — Chief Accounting OfficerSale (S): 362 @ $6.30EDGAR
2025-09-164Paulson Richard A. — President and CEO, DirectorGrant/award (A): 2,800 @ $0 · Sale (S): 1,257 @ $6.43EDGAR
2025-09-164Mano Michael — SVP, General Counsel&SecretaryGrant/award (A): 612 @ $0 · Sale (S): 234 @ $6.43EDGAR
2025-09-164Poulton Stuart — EVP, Chief Development OfficerGrant/award (A): 888 @ $0 · Sale (S): 401 @ $6.43EDGAR
2025-09-164Rangwala Reshma — EVP & Chief Medical OfficerGrant/award (A): 945 @ $0 · Sale (S): 408 @ $6.43EDGAR
2025-09-164Cheng Sohanya Roshan — EVP & Chief Commercial OfficerGrant/award (A): 945 @ $0 · Sale (S): 325 @ $6.43EDGAR
2025-09-164Abate Kristin — Chief Accounting OfficerGrant/award (A): 46 @ $0 · Sale (S): 23 @ $6.43EDGAR
2025-09-044Abate Kristin — Chief Accounting OfficerSale (S): 12 @ $6.78EDGAR
2025-07-304Poulton Stuart — EVP, Chief Development OfficerSale (S): 191 @ $4.37EDGAR
2025-07-234Abate Kristin — Chief Accounting OfficerSale (S): 238 @ $4EDGAR
2025-05-294Greene Barry E — DirectorGrant/award (A): 4,600 (derivative) @ $0EDGAR
2025-05-294PAKIANATHAN DEEPIKA — DirectorGrant/award (A): 4,600 (derivative) @ $0EDGAR
2025-05-294BOHLIN GAREN G — DirectorGrant/award (A): 4,600 (derivative) @ $0EDGAR

Recent 8-K events — Karyopharm Therapeutics Inc.

FiledFormItems reportedSource
2026-09-188-K3.03 — Material Modification to Rights of Security Holders
5.03 — Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year
9.01 — Financial Statements and Exhibits
EDGAR
2026-09-118-K1.01 — Entry into a Material Definitive Agreement
2.04 — Triggering Events That Accelerate or Increase a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement
3.02 — Unregistered Sales of Equity Securities
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-08-318-K8.01 — Other EventsEDGAR
2026-08-138-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-07-318-K8.01 — Other EventsEDGAR
2026-07-178-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain OfficersEDGAR
2026-05-288-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
5.07 — Submission of Matters to a Vote of Security Holders
9.01 — Financial Statements and Exhibits
EDGAR
2026-05-148-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-278-K8.01 — Other EventsEDGAR
2026-03-248-K1.01 — Entry into a Material Definitive Agreement
3.02 — Unregistered Sales of Equity Securities
7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
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