DNLI insider transaction filings

Denali Therapeutics Inc. — 50 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-09-09. Screen DNLI transaction legs live →

Insider transaction summary — last 90 days

2026-06-24 to 2026-09-22, from the filings listed below: 5 Form 4 filings. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By insider — same window

Open-market purchase/sale legs on non-derivative securities, grouped by the filing's reporting owner(s); joint filings appear once. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

InsiderFilingsPurchases (P)Sales (S)Other legs
Thornberry Nancy — Director12 legs · 11,439 sh · $261,929
Schuth Alexander O. — COFO and Secretary22 legs · 5,625 sh · $136,507
Chin Peter Scott — Chief Medical Officer11 leg · 1,654 sh · $36,868
Watts Ryan J. — President and CEO, Director11

Recent Form 4 filings — Denali Therapeutics Inc.

FiledFormInsiderReported transactionsSource
2026-09-094Chin Peter Scott — Chief Medical OfficerSale (S): 1,654 @ $22.29EDGAR
2026-09-044Thornberry Nancy — DirectorSale (S): 10,824 @ $22.85 · Sale (S): 615 @ $23.74EDGAR
2026-09-034Schuth Alexander O. — COFO and SecretarySale (S): 2,768 @ $23.44EDGAR
2026-08-144Watts Ryan J. — President and CEO, DirectorGift (G): 32,220 @ $0EDGAR
2026-08-134Schuth Alexander O. — COFO and SecretarySale (S): 2,857 @ $25.07EDGAR
2026-06-054Van Hauwermeiren Timothy — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054Thornberry Nancy — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054Cook Jennifer E. — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054Krognes Steve E. — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054Schenkein David P — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054Klein Peter S — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054FLATLEY JAY T — DirectorGrant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-06-054BAKER BROS. ADVISORS LP — Director
667, L.P. — Director
Baker Bros. Advisors (GP) LLC — Director
Baker Brothers Life Sciences LP — Director
BAKER FELIX — Director
BAKER JULIAN — Director
Grant/award (A): 6,408 @ $0 · Grant/award (A): 6,408 @ $0 · Grant/award (A): 19,226 (derivative) @ $0 · Grant/award (A): 19,226 (derivative) @ $0EDGAR
2026-01-084Schuth Alexander O. — COFO and SecretarySale (S): 17,218 @ $16.50EDGAR
2026-01-084Watts Ryan J. — President and CEO, DirectorSale (S): 35,198 @ $16.50EDGAR
2026-01-054Schuth Alexander O. — COFO and SecretaryGrant/award (A): 57,700 @ $0 · Grant/award (A): 173,100 (derivative) @ $0EDGAR
2026-01-054Watts Ryan J. — President and CEO, DirectorGrant/award (A): 78,960 @ $0 · Grant/award (A): 236,880 (derivative) @ $0EDGAR
2025-12-154BAKER BROS. ADVISORS LP — Director
667, L.P. — Director
Baker Bros. Advisors (GP) LLC — Director
Baker Brothers Life Sciences LP — Director
BAKER FELIX — Director
BAKER JULIAN — Director
Purchase (P): 190,523 (derivative) @ $17.49 · Purchase (P): 2,095,191 (derivative) @ $17.49EDGAR
2025-11-064Van Hauwermeiren Timothy — DirectorGrant/award (A): 10,632 @ $0 · Grant/award (A): 31,897 (derivative) @ $0EDGAR
2025-09-054Watts Ryan J. — President and CEO, DirectorGift (G): 50,000 @ $0EDGAR
2025-08-144Schuth Alexander O. — COFO and SecretarySale (S): 2,937 @ $13.58EDGAR
2025-08-144Ho Carole — Chief Medical OfficerSale (S): 2,937 @ $13.58 · Sale (S): 806 @ $14.64EDGAR
2025-08-074Ho Carole — Chief Medical OfficerOption exercise (M): 44,655 @ $0.68 · Option exercise (M): 44,655 (derivative) @ $0EDGAR
2025-07-114Watts Ryan J. — President and CEO, DirectorOption exercise (M): 455,282 @ $0.68 · Option exercise (M): 40,000 @ $5.28 · Sale (S): 495,282 @ $15 · Option exercise (M): 455,282 (derivative) @ $0 · Option exercise (M): 40,000 (derivative) @ $0EDGAR
2025-06-054Cook Jennifer E. — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054Thornberry Nancy — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054Krognes Steve E. — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054Schenkein David P — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054Klein Peter S — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054Tessier-Lavigne Marc — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054FLATLEY JAY T — DirectorGrant/award (A): 6,037 @ $0 · Grant/award (A): 18,111 (derivative) @ $0EDGAR
2025-06-054BAKER BROS. ADVISORS LP — Director
667, L.P. — Director
Baker Bros. Advisors (GP) LLC — Director
Baker Brothers Life Sciences LP — Director
BAKER FELIX — Director
BAKER JULIAN — Director
Grant/award (A): 10,565 @ $0 · Grant/award (A): 10,565 @ $0 · Grant/award (A): 31,695 (derivative) @ $0 · Grant/award (A): 31,695 (derivative) @ $0EDGAR
2025-01-084Ho Carole — Chief Medical OfficerSale (S): 12,255 @ $20.22 · Sale (S): 2,907 @ $20.81EDGAR
2025-01-084Schuth Alexander O. — COFO and SecretarySale (S): 12,255 @ $20.22 · Sale (S): 2,907 @ $20.81EDGAR
2025-01-084Watts Ryan J. — President and CEO, DirectorSale (S): 29,266 @ $20.22 · Sale (S): 7,650 @ $20.81EDGAR
2025-01-084Krognes Steve E. — DirectorSale (S): 3,339 @ $20.81EDGAR
2025-01-074Watts Ryan J. — President and CEO, DirectorGrant/award (A): 54,180 @ $0 · Grant/award (A): 162,540 (derivative) @ $0EDGAR
2025-01-074Schuth Alexander O. — COFO and SecretaryGrant/award (A): 54,180 @ $0 · Grant/award (A): 162,540 (derivative) @ $0EDGAR
2025-01-074Ho Carole — Chief Medical OfficerGrant/award (A): 54,180 @ $0 · Grant/award (A): 162,540 (derivative) @ $0EDGAR
2025-01-034Krognes Steve E. — DirectorSale (S): 30,000 @ $20.25EDGAR
2025-01-034SATO VICKI L — DirectorSale (S): 3,080 @ $20.91EDGAR
2024-12-314Schuth Alexander O. — COFO and SecretaryOption exercise (M): 6,708 @ $5.28 · Option exercise (M): 6,708 (derivative) @ $0EDGAR
2024-11-274Ho Carole — Chief Medical OfficerOption exercise (M): 17,845 @ $0.68 · Option exercise (M): 17,845 (derivative) @ $0EDGAR
2024-11-264Schuth Alexander O. — COFO and SecretaryOption exercise (M): 20,516 @ $0.68 · Option exercise (M): 20,516 (derivative) @ $0EDGAR
2024-11-134Schenkein David P — DirectorOption exercise (M): 47,165 @ $18 · Sale (S): 27,129 @ $32.09 · Sale (S): 32,312 @ $32.87 · Option exercise (M): 47,165 (derivative) @ $0EDGAR
2024-11-124Schuth Alexander O. — COFO and SecretaryOption exercise (M): 15,558 @ $5.28 · Sale (S): 12,333 @ $29.68 · Sale (S): 2,925 @ $30.72 · Sale (S): 300 @ $31.29 · Option exercise (M): 15,558 (derivative) @ $0EDGAR
2024-11-124SATO VICKI L — DirectorSale (S): 1,020 @ $30EDGAR
2024-11-054SATO VICKI L — DirectorSale (S): 3,080 @ $27.07EDGAR
2024-10-224Watts Ryan J. — President and CEO, DirectorOption exercise (M): 40,000 @ $0.68 · Sale (S): 40,000 @ $27.69 · Option exercise (M): 40,000 (derivative) @ $0EDGAR
2024-10-024Krognes Steve E. — DirectorSale (S): 30,000 @ $29.03EDGAR

Recent 8-K events — Denali Therapeutics Inc.

FiledFormItems reportedSource
2026-08-068-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-07-288-K2.01 — Completion of Acquisition or Disposition of Assets
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-188-K1.01 — Entry into a Material Definitive Agreement
7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-048-K5.07 — Submission of Matters to a Vote of Security Holders
9.01 — Financial Statements and Exhibits
EDGAR
2026-05-228-K7.01 — Regulation FD DisclosureEDGAR
2026-05-078-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-04-038-K1.02 — Termination of a Material Definitive Agreement
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-318-K2.03 — Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant
7.01 — Regulation FD Disclosure
EDGAR
2026-03-258-K7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2026-02-268-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
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