AMLX insider transaction filings

Amylyx Pharmaceuticals, Inc. — 50 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-09-14. Screen AMLX transaction legs live →

Insider transaction summary — last 90 days

2026-06-24 to 2026-09-22, from the filings listed below: 12 Form 4 filings. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By insider — same window

Open-market purchase/sale legs on non-derivative securities, grouped by the filing's reporting owner(s); joint filings appear once. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

InsiderFilingsPurchases (P)Sales (S)Other legs
Cohen Joshua B — Co-Chief Executive Officer, Director22 legs · 30,464 sh · $980,5041
Klee Justin B. — Co-Chief Executive Officer, Director22 legs · 30,464 sh · $980,2631
Mazzariello Gina — Chief Legal Officer34 legs · 39,536 sh · $848,3741
FRATES JAMES M — Chief Financial Officer22 legs · 10,810 sh · $349,8211
Bedrosian Camille L — Chief Medical Officer22 legs · 10,028 sh · $324,8681
Firestone Karen — Director14

Recent Form 4 filings — Amylyx Pharmaceuticals, Inc.

FiledFormInsiderReported transactionsSource
2026-09-144Cohen Joshua B — Co-Chief Executive Officer, DirectorSale (S): 29,545 @ $32.16 · Sale (S): 919 @ $33.15EDGAR
2026-09-144Klee Justin B. — Co-Chief Executive Officer, DirectorSale (S): 29,025 @ $32.13 · Sale (S): 1,439 @ $33.16EDGAR
2026-09-144Mazzariello Gina — Chief Legal OfficerSale (S): 9,525 @ $32.46 · Sale (S): 11 @ $33.34EDGAR
2026-09-144FRATES JAMES M — Chief Financial OfficerSale (S): 9,768 @ $32.27 · Sale (S): 1,042 @ $33.23EDGAR
2026-09-144Bedrosian Camille L — Chief Medical OfficerSale (S): 7,947 @ $32.21 · Sale (S): 2,081 @ $33.09EDGAR
2026-09-024Firestone Karen — DirectorOption exercise (M): 25,000 @ $1.76 · Option exercise (M): 25,000 @ $5.05 · Option exercise (M): 25,000 (derivative) @ $0 · Option exercise (M): 25,000 (derivative) @ $0EDGAR
2026-08-204Mazzariello Gina — Chief Legal OfficerGrant/award (A): 21,284 @ $0EDGAR
2026-08-204Klee Justin B. — Co-Chief Executive Officer, DirectorGrant/award (A): 60,039 @ $0EDGAR
2026-08-204FRATES JAMES M — Chief Financial OfficerGrant/award (A): 22,807 @ $0EDGAR
2026-08-204Cohen Joshua B — Co-Chief Executive Officer, DirectorGrant/award (A): 60,039 @ $0EDGAR
2026-08-204Bedrosian Camille L — Chief Medical OfficerGrant/award (A): 22,807 @ $0EDGAR
2026-07-134Mazzariello Gina — Chief Legal OfficerSale (S): 15,000 @ $18.32 · Sale (S): 15,000 @ $17.61EDGAR
2026-06-084Zeiher Bernhardt G — DirectorGrant/award (A): 24,372 (derivative) @ $0EDGAR
2026-06-084Firestone Karen — DirectorGrant/award (A): 24,372 (derivative) @ $0EDGAR
2026-06-084FONTEYNE PAUL R. — DirectorGrant/award (A): 24,372 (derivative) @ $0EDGAR
2026-06-084Quimi Daphne — DirectorGrant/award (A): 24,372 (derivative) @ $0EDGAR
2026-06-084MILNE GEORGE M JR — DirectorGrant/award (A): 24,372 (derivative) @ $0EDGAR
2026-05-264Firestone Karen — DirectorPurchase (P): 3,800 @ $13.51EDGAR
2026-03-094Cohen Joshua B — Co-Chief Executive Officer, DirectorGrant/award (A): 248,865 @ $0 · Grant/award (A): 373,295 (derivative) @ $0EDGAR
2026-03-094Mazzariello Gina — Chief Legal OfficerGrant/award (A): 74,660 @ $0 · Grant/award (A): 111,990 (derivative) @ $0EDGAR
2026-03-094Klee Justin B. — Co-Chief Executive Officer, DirectorGrant/award (A): 248,865 @ $0 · Grant/award (A): 373,295 (derivative) @ $0EDGAR
2026-03-094Bedrosian Camille L — Chief Medical OfficerGrant/award (A): 95,990 @ $0 · Grant/award (A): 143,985 (derivative) @ $0EDGAR
2026-03-094FRATES JAMES M — Chief Financial OfficerGrant/award (A): 95,990 @ $0 · Grant/award (A): 143,985 (derivative) @ $0EDGAR
2026-03-044Klee Justin B. — Co-Chief Executive Officer, DirectorSale (S): 29,282 @ $14.47EDGAR
2026-03-044Cohen Joshua B — Co-Chief Executive Officer, DirectorSale (S): 29,282 @ $14.48EDGAR
2026-03-044Mazzariello Gina — Chief Legal OfficerSale (S): 6,844 @ $14.52EDGAR
2026-03-044Bedrosian Camille L — Chief Medical OfficerSale (S): 6,461 @ $14.58EDGAR
2026-03-044FRATES JAMES M — Chief Financial OfficerSale (S): 7,909 @ $14.52EDGAR
2026-02-254Mazzariello Gina — Chief Legal OfficerSale (S): 3,419 @ $14.14EDGAR
2026-02-044Cohen Joshua B — Co-Chief Executive Officer, DirectorSale (S): 15,500 @ $14.68EDGAR
2026-02-044Mazzariello Gina — Chief Legal OfficerSale (S): 3,448 @ $14.65EDGAR
2026-02-044Klee Justin B. — Co-Chief Executive Officer, DirectorSale (S): 15,500 @ $14.69EDGAR
2026-02-044FRATES JAMES M — Chief Financial OfficerSale (S): 3,557 @ $14.65EDGAR
2026-01-204Cohen Joshua B — Co-Chief Executive Officer, DirectorOption exercise (M): 197,182 @ $7.57 · Sale (S): 136,193 @ $13.59 · Option exercise (M): 2,818 @ $7.57 · Sale (S): 1,974 @ $13.83 · Option exercise (M): 197,182 (derivative) @ $0 · Option exercise (M): 2,818 (derivative) @ $0EDGAR
2026-01-204Klee Justin B. — Co-Chief Executive Officer, DirectorOption exercise (M): 197,153 @ $7.57 · Sale (S): 136,193 @ $13.58 · Option exercise (M): 2,847 @ $7.57 · Sale (S): 1,995 @ $13.89 · Option exercise (M): 197,153 (derivative) @ $0 · Option exercise (M): 2,847 (derivative) @ $0EDGAR
2026-01-144MILNE GEORGE M JR — DirectorGift (G): 17,780 @ $0EDGAR
2026-01-084Cohen Joshua B — Co-Chief Executive Officer, DirectorSale (S): 7,715 @ $11.09EDGAR
2026-01-084Klee Justin B. — Co-Chief Executive Officer, DirectorSale (S): 7,715 @ $11.09EDGAR
2026-01-084FRATES JAMES M — Chief Financial OfficerSale (S): 3,326 @ $11.11EDGAR
2025-12-234Firestone Karen — DirectorPurchase (P): 8,100 @ $12.45EDGAR
2025-12-034Bedrosian Camille L — Chief Medical OfficerSale (S): 6,580 @ $14.35EDGAR
2025-10-024Klee Justin B. — Co-Chief Executive Officer, DirectorSale (S): 29,775 @ $14.37 · Sale (S): 200 @ $15.01EDGAR
2025-10-024Mazzariello Gina — Chief Legal OfficerSale (S): 8,828 @ $14.58EDGAR
2025-10-024Cohen Joshua B — Co-Chief Executive Officer, DirectorSale (S): 29,733 @ $14.34 · Sale (S): 200 @ $15.00EDGAR
2025-10-024Bedrosian Camille L — Chief Medical OfficerSale (S): 12,039 @ $14.58EDGAR
2025-10-024FRATES JAMES M — Chief Financial OfficerSale (S): 10,558 @ $14.65EDGAR
2025-08-144Mazzariello Gina — Chief Legal OfficerSale (S): 15,000 @ $8.07 · Sale (S): 15,000 @ $8.34EDGAR
2025-06-094Zeiher Bernhardt G — DirectorGrant/award (A): 25,000 (derivative) @ $0EDGAR
2025-06-094Quimi Daphne — DirectorGrant/award (A): 25,000 (derivative) @ $0EDGAR
2025-06-094MILNE GEORGE M JR — DirectorGrant/award (A): 25,000 (derivative) @ $0EDGAR

Recent 8-K events — Amylyx Pharmaceuticals, Inc.

FiledFormItems reportedSource
2026-09-088-K1.01 — Entry into a Material Definitive AgreementEDGAR
2026-08-208-K1.01 — Entry into a Material Definitive Agreement
9.01 — Financial Statements and Exhibits
EDGAR
2026-08-188-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-08-188-K8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-08-068-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-048-K5.07 — Submission of Matters to a Vote of Security HoldersEDGAR
2026-05-078-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-248-K7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-038-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-01-088-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
Need this as JSON? GET https://api.filingpulse.io/v1/insider-trades?ticker=AMLX returns every filing on this page — normalized, with footnotes and derivative legs — and webhooks push new ones to you in seconds. API docs →